Episodes
- January
- ENT: "In a Mirror, Darkly"
- ENT: "In a Mirror, Darkly, Part II"
- ENT: "Demons"
- ENT: "Terra Prime"
Events
- The Coalition of Planets is founded. The founding members include Humans, Vulcans, Andorians, Tellarites, Rigelians, Denobulans and the Coridanites. (ENT: "Demons")
- Decontamination of Cold Station 12 is completed. (ENT: "The Augments")
- In the alternate timeline where Earth was destroyed by the Xindi, Enterprise begins leading a fugitive convoy to the Ceti Alpha system. (ENT: "Twilight")
- In the mirror universe, the ISS Enterprise travels into Tholian space in search of a Terran vessel - the Template:ShipClass USS Defiant. The Enterprise is destroyed and most of the senior staff retrieve the Defiant. (ENT: "In a Mirror, Darkly")
| 2154 | 22nd century 2150s |
2156 |