Dark matter nebulae are accumulations of dark matter, that are difficult to detect on sensors unless illuminated by metreon particles. (ENT: "First Flight")
When he was a guest aboard the Vulcan starship Yarahla, Captain Jonathan Archer assisted on their study of a dark matter nebula. (ENT: "Breaking the Ice")
A second dark matter nebula was observed by Captain Archer and Subcommander T'Pol in March of 2153. It was named the Robinson Nebula in honor of the late A.G. Robinson. (ENT: "First Flight")
In 2367, the USS Enterprise-D explored the previously uncharted Mar Oscura Nebula. The nebula was littered with spatial deformations, making travel hazardous. (TNG: "In Theory")
In 2371, the USS Voyager encountered trianic energy beings known as the Komar in a dark matter nebula in the Delta Quadrant. (VOY: "Cathexis")
Neelix said that he once lost a warp nacelle on a ship he was piloting through a dark matter nebula. (VOY: "Threshold")
An uncharted dark matter nebula was located in Cardassian space, near a Dominion ketracel-white storage facility destroyed by Captain Benjamin Sisko and his crew in 2374. Sisko ordered his damaged ship into the nebula to escape several pursuing Jem'Hadar fighters, whereupon they crashed on an uncharted planet. (DS9: "Rocks and Shoals")