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Extragalactic species were those species located or originating from outside of the Milky Way.
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- Space amoeba
- Sphere Builders
The androids of Planet Mudd were said to be from the Andromeda Galaxy. (TOS: "I, Mudd").
Spock also speculated that the Neural parasites encountered on Deneva might have originated in another galaxy.
Onaya claimed she could spot a creative soul "a galaxy away". If taken literally, this might indicated that she had at least traveled outside the galaxy, possibly having originated there.