Honolulu was a city located on the island of O'ahu in the Hawaiian island chain on Earth.
After traveling back to 1930 to await the arrival of Leonard McCoy, James Kirk referred to Honolulu as one of the countless locations McCoy may arrive in. (TOS: "The City on the Edge of Forever")
In the early 21st century, Kelleye N. Raymond, the daughter of Cheryl G. Raymond and Wil W. Lachance Raymond, was born in this city. (TNG: "The Neutral Zone")