The multispatial probe was an advanced probe designed by Lieutenant Commander Tuvok of the USS Voyager in 2375. It was equipped with unimatrix shielding.
On the probe's first flight, a Malon freighter attempted to steal it. To stop them, the Voyager crew sent the probe into the atmosphere of a class 6 gas giant. The probe was later retrieved by the newly constructed Delta Flyer, ahead of a competing salvage team sent by Malon Controller Vrelk. (VOY: "Extreme Risk")
Later in 2375, the Voyager crew used the multispatial probe to explore a pocket of subspace beyond a subspace sinkhole, where a shuttlecraft carrying Tuvok, Tom Paris, and the Doctor had crashed. The probe subsequently served as a transporter relay, allowing their rescue. (VOY: "Gravity")
In 2376, B'Elanna Torres piloted shuttle on a solo mission to retrieve the multispatial probe, after it entered an ion storm. (VOY: "Barge of the Dead")