Nona was a Kahn-ut-tu woman and the wife of Tyree, leader of the Hill People on the planet Neural. Nona possessed mystical powers that kept Tyree under her spell. When rival villagers obtain flintlock guns from the Klingons, Nona wanted Tyree to get the same weapons so they could be stronger than their enemies. Tyree wished to follow the path of peace.
In 2268, she helped cure James T. Kirk after he was attacked by a Mugato. She saw McCoy use a phaser to heat rocks to keep Kirk warm, and she saw this as a weapon she could use to obtain power. She refused to cure Kirk until Tyree told her who they were. Nona wanted Kirk to arm her people as a reward for curing him but he refused.
Nona, believing that the rival clan would become rulers of the planet, decided to betray Tyree. She stole the phaser and sought out Apella, the leader of the rival faction. She was intercepted by his men, but when they saw Tyree and Kirk approaching, they believed it was a trap and stabbed her to death. (TOS: "A Private Little War")