The parietal lobe was the part of the brain that was located in the middle of the cerebral hemispheres. It aided in integrating sensory information.
In 2368, Seven of Nine injected three other Borg drones with nanoprobes that created new organic interlink nodes in their left parietal lobes. This resulted a new neural link between them, which persisted even after the three were later freed from the Borg Collective. (VOY: "Survival Instinct")
Doctor Crusher found a small structural defect in Picard's parietal lobe in 2370 that could lead to a number of neurological disorders, including Irumodic syndrome. The defect was so small it required a level-4 neurographic scan to be located. (TNG: "All Good Things...")
When the Pah-wraith-possessed Keiko O'Brien fell down from the upper level of the Promenade in 2373, she suffered a broken femur and a hairline fracture of the right parietal lobe. (DS9: "The Assignment")