Serpent might refer to:
- Aldebaran serpent, a three-headed snake-like creature from the Aldebaran system.
- "How Sharper Than a Serpent's Tooth", the second season Animated Series episode.
- Kos'karii, a mythological Klingon serpent.
- Serpent of Xol, creature from Klingon legends.
- Serpent women, otherwise known as female U'tani.
- Serpent's Ridge, a location on Bajor.
- Snake, the reptilian creature.
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