The Tomed Incident was a terrible confrontation between the United Federation of Planets and the Romulan Star Empire in 2311 that cost thousands of lives. The incident led to the signing of the Treaty of Algeron, which banned Federation research into or use of any cloaking device, and led to the withdrawal of the Romulan government from interstellar affairs until 2364. (TNG: "The Neutral Zone", "The Pegasus", "The Defector"; ENT: "These Are the Voyages...")
The Tomed Incident was the primary focus of the Lost Era novel, Serpents Among the Ruins. In the novel, the warbird Tomed crashes into an asteroid, housing a Federation base, at high warp, and because the containment of its quantum singularity had failed, the massive explosion which results distorts the fabric of spacetime and wipes out numerous Starfleet outposts, as well as the USS Agamemnon. However, while the "official" casualties (including Esteban Rodriguez and Tom Paris's grandfather) number in the thousands, the actual death toll is six, all Romulan; the Agamemnon and the bases were empty, rigged to emit false lifesigns, the thousands of Starfleet personnel listed as killed in the attack already dead - their deaths in the past year having been covered up - and records fabricated to appear that they had been stationed there.
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